Crohn Disease

Overview

4.8 out of 5 (428 Reviews)

Credits

2.50

Post-Assessment Questions

8

Start Date

1 Sep 2023

Last Review Date

1 Dec 2025

Expiration Date

31 Aug 2026

Estimated Time To Finish

150 Minutes


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Activity Description

Crohn disease and ulcerative colitis are distinct disorders collectively referred to as inflammatory bowel disease. Crohn disease is multifactorial, involving genetic susceptibility, dysregulated immune responses, and environmental triggers such as smoking. Transmural inflammation driven by aberrant helper T-cell activity and cytokine signaling leads to noncaseating granuloma formation and progressive tissue injury. The condition can affect any segment of the gastrointestinal tract but most commonly involves the terminal ileum and proximal colon.

Patients who develop Crohn disease often present with abdominal pain, chronic diarrhea, weight loss, and fatigue. Extraintestinal manifestations, including arthropathy and skin lesions, may also occur. Diagnosis is established using endoscopy, histopathology, and cross-sectional imaging. Management includes anti-inflammatory agents, immunomodulators, biologic therapy, and surgery for refractory disease or complications such as strictures, fistulas, and abscesses. The disease follows a chronic, relapsing course, and early recognition with appropriate treatment is essential to reduce morbidity and preserve quality of life.

This activity for healthcare workers is designed to enhance learners' competence in evaluating and managing Crohn disease. Participants will gain deeper insights into the condition's etiology, risk factors, pathophysiology, clinical presentation, and evidence-based diagnostic and therapeutic approaches. Improved proficiency will equip learners to collaborate effectively with interprofessional teams caring for individuals with Crohn disease.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the signs and symptoms indicative of Crohn disease.

  • Create a clinically sound diagnostic strategy to evaluate a patient suspected to have Crohn disease.

  • Develop a personalized, evidence-based plan for managing Crohn disease and mitigating its potential sequelae.

  • Collaborate with the interprofessional team to educate, treat, and monitor patients with Crohn disease to improve long-term outcomes.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Physicians and Physician Associates: StatPearls, LLC designates this enduring material for a maximum of 2.50 AMA PRA Category 1 Credit(s)TM. Physicians and PAs should only claim credit commensurate with the extent of their participation in the activity.

American Board of Anesthesiology: This activity contributes to the CME component of the American Board of Anesthesiology’s redesigned Maintenance of Certification in AnesthesiologyTM (MOCA®) program, known as MOCA 2.0®. Please consult the ABA website, www.theABA.org, for a list of all MOCA 2.0 requirements.

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List of extraintestinal manifestations should be expanded.

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