Twin-to-Twin Transfusion Syndrome

Overview

4.5 out of 5 (2 Reviews)

Credits

1.00

Post-Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

31 Jan 2026

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


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Activity Description

Twin-to-twin transfusion syndrome (TTTS) is a serious complication unique to monochorionic twin pregnancies, caused by unbalanced placental blood flow between fetuses who share a single placenta. There are numerous possible outcomes of this condition, ranging from stabilization to fetal demise. It is important to screen for the development of this condition to ensure appropriate management and treatment can be undertaken. This activity reviews the embryology of twinning, classification of twin gestations, and the pathophysiology underlying TTTS.

Learners will examine how the timing of zygotic splitting determines chorionicity and amnionicity, including dichorionic-diamniotic (DCDA), monochorionic-diamniotic (MCDA), and monochorionic-monoamniotic (MCMA) pregnancies. Given that more than 95% of MCDA twins share intertwin placental circulation, participants will gain insight into why these gestations are at high risk for TTTS. The course emphasizes the diagnostic criteria for TTTS and specialized diagnostic considerations for monoamniotic twins. The value of interprofessional collaboration in optimizing outcomes for TTTS is highlighted. Coordinated roles among maternal–fetal medicine specialists, obstetricians, sonographers, neonatologists, surgeons, nurses, and allied health professionals to support early diagnosis, fetal intervention, perinatal management, and family counseling are explored.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the underlying etiology and pathophysiologic mechanisms of twin-to-twin transfusion syndrome.

  • Apply standardized evidence-based criteria to accurately diagnose and stage twin-to-twin transfusion syndrome across clinical settings.

  • Improve clinical decision-making by integrating consensus recommendations and emerging evidence into the management of twin-to-twin transfusion syndrome.

  • Collaborate with an interprofessional healthcare team to optimize coordinated management and patient counseling for twin-to-twin transfusion syndrome.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.00 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Brian K. on 10/2/2022

Casey H. on 3/13/2026

Unlimited Nurse CE

Stay up to date on the latest medical knowledge with 6345 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7566.5 hours of CE.

Single Activity

Take this single activity

$25 1 activity

6 Month Unlimited Nurse CE

Access to all the Unlimited Nurse CE activities in all specialties.

$89 per half year per user

1 Year Unlimited Nurse CE

Access to all the Unlimited Nurse CE activities in all specialties.

$139 per 1 year per user