Ace The SPEX Exam

Be prepared for the Federation of State Medical Boards® with 4,821 Questions that our experts have selected to simulate the real exam.

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About the Question Bank

Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are based on our experts review of the Federation of State Medical Boards® topics. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.

Multiple-choice questions

We have 4,821 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 2,790 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to system and clinical SPEX Student subject areas. In addition, you will have access to a pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.

Achieve top scores

The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 1,543 authors and 90 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.

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SPEX Exam Overview

  • How many hours is the SPEX Exam?

    The SPEX Exam is 6 hours.

  • How many questions is the SPEX Exam?

  • What topics are covered on the SPEX Exam?

SPEX Exam MCQs (4,821)

Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:

Level 1

22 Questions

Level 2

469 Questions

Level 3

3,515 Questions

Level 4

815 Questions

  • Allergy and Immunology - 216 questions
  • Cardiovascular - 1305 questions
  • Musculoskeletal - 866 questions
  • Ears Nose and Throat - 255 questions
  • Endocrine and Metabolism - 605 questions
  • Ophthalmology - 220 questions
  • Gastrointestinal and Nutrition - 1052 questions
  • Renal, Urinary and Electrolytes - 544 questions
  • Human Growth and Development - 173 questions
  • Gynecologic - 201 questions
  • Hematology and Oncology - 839 questions
  • Infectious Diseases - 1253 questions
  • Skin & Subcutaneous Tissue - 489 questions
  • Nervous - 1140 questions
  • Pregnancy, Childbirth & Puerperium - 193 questions
  • Psychiatric/Behavioral & Substance Use Disorder - 463 questions
  • Pulmonary & Critical Care - 770 questions
  • Poisoning & Environmental Exposure - 651 questions
  • Biostatistics and Epidemiology - 164 questions
  • Dental - 29 questions
  • Reproductive - 77 questions
  • Sexuality and Gender - 17 questions
  • Social Sciences (Ethics/Legal/Professional) - 95 questions
  • Traumatic Injuries - 282 questions
  • Manage Care and Comply Regulations - 121 questions
  • Promote Safety and Minimize Infection - 116 questions
  • Health Promotion & Maintenance (Prevent Problems) - 296 questions
  • Basic Care and Comfort (Assist Daily Living Tasks) - 37 questions
  • Pharm/Parenteral Therapy (Drugs/Vital Signs) - 945 questions
  • Reduction Risk (Post Procedure) - 83 questions
  • Physiological Adaptation (Care Ill Patients) - 3511 questions
  • Psychosocial (Mental Health Patient/Family) - 265 questions
  • Professional Practice - 106 questions
  • Process (Analysis, Assess, Eval, Implement, Plan) - 4367 questions
  • Caring (Hope and Support) - 43 questions
  • Communication/Documentation (Oral, Written, EMR) - 55 questions
  • Teaching/Learning (Promotes Behavior Change) - 46 questions
  • Culture/Spiritualilty (Beliefs, Practices, Ethics) - 18 questions
  • Causes - 2917 questions
  • Classification - 453 questions
  • Differential - 2994 questions
  • Evaluation Diagnostic Tests - 1524 questions
  • Evaluation Lab - 1650 questions
  • Evaluation Monitoring - 508 questions
  • Evaluation Nuclear Medicine - 14 questions
  • Evaluation Procedures - 930 questions
  • Evaluation Radiologic - 1434 questions
  • Health Maint Prevention Public Health - 226 questions
  • History Physical - 5694 questions
  • Legal - 51 questions
  • Patient Education - 339 questions
  • Prognosis Complications - 2826 questions
  • Toxicology - 299 questions
  • Treatment Medical - 2832 questions
  • Treatment Occupation/Physical Therapy - 60 questions
  • Treatment Prehospital/EMS/Disaster - 59 questions
  • Treatment Radiation - 22 questions
  • Treatment Rehabilitation - 35 questions
  • Treatment Surgical - 641 questions
  • Healthcare Ethics - 65 questions
  • Clinical Education - 117 questions
  • Environmental - 33 questions
  • Palliative - 35 questions
  • Treatment Manipulative - 13 questions
  • Airway Management - 51 questions
  • Pain Management - 68 questions
  • Sedation and Analgesic Management - 17 questions
  • Organ and Tissue Donation - 5 questions
  • Ventilatory Management - 24 questions
  • Research and Evidence-Based Medicine - 59 questions
  • Resource Utilization - 21 questions
  • Vulnerable Populations - 78 questions
  • Therapeutics (Drug treatment) - 2832 questions
  • Biostatics and Calculations - 29 questions
  • Drug Information - 1026 questions
  • Pharmaceutics (Safely dosing medications) - 395 questions
  • Pharmacokinetics (Drug movement in body) - 238 questions

SPEX Exam Articles (2,790)

We link each review question to its peer-reviewed, PubMed-indexed article from StatPearls authors and editors.
We make it easy for you to reinforce topic areas you excel at and fill knowledge gaps with source material.

To preserve the impartiality and independence required of all accredited board certification programs, StatPearls has no official connection to any board or certification exam.